Heart Conditions | RM SIMVASTATIN 20 MG TAB | RiteMED

RM SIMVASTATIN 20 MG TAB

Antihyperlipidemic

Contents

Each tablet contains:

 

Simvastatin 20 mg or 40 mg

Price

(Vat-exempted)

P 14.32

Price Comparison

Check
RM SIMVASTATIN 20 MG TAB
(Vat-exempted)
ZOCOR 20 MG TAB
14.32 35.00

Product Details

What is this medicine used for?

 

It is used in patients with hyperlipidemia, coronary heart disease and hypercholesterolemia to decrease the risk of fatal and non-fatal myocardial infarction and decrease the incidence of stroke and transient ischemic attacks.

 

How much and how often should you use this medicine?

 

Coronary Heart Disease

 

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  • Initial Dose: 20 mg once daily at bedtime
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  • May be increased at intervals of not less than 4 weeks to a maximum of 80 mg
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  • once daily given as a single dose at bedtime.
  •  

 

Hyperlipidemia

 

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  • Initial Dose: 20 mg once daily at bedtime
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  • Patients who require only a moderate reduction of LDL-C may be started at 10 mg once daily at bedtime.
  •  

 

Homozygous Familial Hypercholesterolemia

 

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  • Initial Dose: 40 mg once daily at bedtime or 80 mg/day in 3 divided doses of 20 mg, 20mg and 40 mg given in the morning, afternoon and evening, respectively.
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Renal Insufficiency

 

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  • Initial Dose: 5 mg once daily at bedtime with close monitoring
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  • Initiating therapy in patients with severe renal insufficiency (creatinine clearance <30 mL/min) at a dose above 10 mg/day should be considered carefully and implemented cautiously.
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  • Dose modification should not be necessary in patients with mild to moderate renal impairment because simvastatin does not undergo substantial renal excretion.
  •  

 

Or, as prescribed by a physician.

 

Contraindications

 

  •  
  • Erythromycin, Clarithromycin: increased risk of muscle pain and weakness
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  • Niacin: increased risk of muscle pain and weakness
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  • Grapefruit juice: increased risk of muscle pain and weakness
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  • Itraconazole, Ketoconazole: increased risk of muscle pain and weakness
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  • Nelfinavir, Ritonavir, Saquinavir: increased risk of liver damage
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  • Diagnosed with liver disease, rhabdomyolysis
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Availability

 

  •  
  • Simvastatin 20 mg Tablet – Box of 100’s (in blister foil by 10’s)
  •  
  • Simvastatin 40 mg Tablet – Box of 100’s (in blister foil by 10’s)
  •