Product Details
What is this medicine used for?
Adults
- For the treatment of the following uncomplicated and complicated infections caused by susceptible microorganisms, when oral antibiotic therapy is not possible or not reliable:
- Urinary tract and kidney infections including cystitis, pyelonephritis
- Lower respiratory tract infections including acute exacerbations of chronic bronchitis
- Nosocomial pneumonia including hospital-acquired, ventilator-associated, and healthcare-associated pneumonia
- Acute sinusitis, middle ear infection (otitis media) and eye infections
- Skin and skin structure infections
- Septicemia
- Intra-abdominal infections (the anaerobic component should be covered by an appropriate antibacterial agent) including infections of the gastrointestinal tract or of the biliary tract, peritonitis
- Bone and joint infections including osteomyelitis
- Genital infections including adnexitis, chronic bacterial prostatitis
- To reduce the incidence or progression of inhalational anthrax following exposure to aerosolized Bacillus anthracis (ciprofloxacin serum concentrations achieved in humans serve as surrogate endpoint reasonably likely to predict clinical benefit and provide basis for this indication).
- As an empirical therapy for febrile neutropenic patients
- As a prophylaxis in infections or imminent risk of infection in patients whose immune system has been weakened (e.g., patients on immunosuppressants or have neutropenia)
- For selective intestinal decontamination in immunosuppressed patients
Children and Adolescents:
Complicated urinary tract infections and pyelonephritis due to Escherichia coli in patients 1 to 17 years old.
Acute pulmonary exacerbations of cystic fibrosis associated with Pseudomonas aeruginosa infection in patients 5 to 17 years old
Inhalational anthrax (post-exposure)
How much and how often should you use this medicine?
Ciprofloxacin 500 mg Tablet
|
Infection |
Type of Severity |
Unit Dose |
Frequency |
Usual |
|
Urinary Tract |
Acute Uncomplicated |
250 mg |
q 12 h |
3 Days |
|
Mild/Moderate |
250 mg |
q 12 h |
7 to 14 Days |
|
|
Severe/Complicated |
500 mg |
q 12 h |
7 to 14 Days |
|
|
Chronic |
Mild/Moderate |
500 mg |
q 12 h |
28 Days |
|
Lower |
Mild/Moderate |
500 mg |
q 12 h |
7 to 14 Days |
|
Severe/Complicated |
750 mg |
q 12 h |
7 to 14 Days |
|
|
Acute Sinusitis |
Mild/Moderate |
500 mg |
q 12 h |
10 Days |
|
Skin and Skin Structure |
Mild/Moderate |
500 mg |
q 12 h |
7 to 14 Days |
|
Severe/Complicated |
750 mg |
q 12 h |
7 to 14 Days |
|
|
Bone and Joint |
Mild/Moderate |
500 mg |
q 12 h |
≥4 to 6 Days |
|
Severe/Complicated |
750 mg |
q 12 h |
≥ 4 to 6 Days |
|
|
Intra-Abdominal* |
Complicated |
500 mg |
q 12 h |
7 to 14 Days |
|
Infectious Diarrhea |
Mild/Moderate/Severe |
500 mg |
q 12 h |
5 to 7 Days |
|
Typhoid Fever |
Mild/Moderate |
500 mg |
q 12 h |
10 Days |
|
Urethral and Cervical |
Uncomplicated |
250 mg |
Single dose |
Single dose |
|
Inhalational anthrax (post-exposure)** |
Adult
Pediatric (18 years old & below) |
500 mg
15mg/Kg/dose, not to exceed 500 mg/dose |
q 12 h
q 12 h |
60 Days
60 Days |
Patient Information
Ciprofloxacin may or may not be taken with meals. However, if taken on an empty stomach, the drug is absorbed more rapidly.
Do not take Ciprofloxacin with dairy products (like milk or yogurt) or calcium-fortified juices alone since absorption of ciprofloxacin may be significantly reduced; however, ciprofloxacin may be taken with a meal that contain these products.
Drink fluids liberally.
Administer Ciprofloxacin at least 2 hours before or 6 hours after magnesium/aluminum antacids or sucralfate, didanosine chewable/buffered tablets or pediatric powder for oral solution or other products containing calcium, iron or zinc.
Contraindications
- Hypersensitivity to Ciprofloxacin or any ingredient in the product
- Chloramphenicol: both drugs have decreased effects when taken together
- Foscarnet: may cause seizures
- Warfarin and other oral anticoagulants: increased risk of bleeding
- Tinazidine: increased risk of severe blood pressure lowering and sedation
- Ropinirole: increased risk of ropinirole toxicity
- Dairy products, milk: may reduce the absorption of ciprofloxacin
- Breastfeeding: Ciprofloxacin is excreted in breast milk
Availability
- Ciprofloxacin 500 mg Tablet – box by 100’s (in blister foil by 10’s)
