Product Details
What is this medicine used for?
For the treatment of lower respiratory tract infections, skin and soft tissue infections, urinary tract infections, gonorrhea, pelvic-inflammatory disease, bone and joint infections, and intra-abdominal infections caused by susceptible pathogens.
How much and how often should you use this medicine?
Ceftriaxone may be administered intravenously or intramuscularly.
ADULTS:
Usual adult daily dose: 1 to 2 g given once a day (or in equally divided doses twice a day) depending on the type and severity of infection. The total daily dose should not exceed 4 g.
Treatment of uncomplicated gonococcal infection: 250 mg IM as a single dose
Surgical infection prophylaxis: 1 g IV 0.5 to 2 hours before surgery
Children:
Treatment of skin and skin structure infections: 50 to 75 mg/kg once a day (or in equally divided doses twice a day). Total daily dose should not exceed 2 g.
Treatment of acute bacterial otitis media: 50 mg/kg IM as a single dose (not to exceed 1 g)
Treatment of serious miscellaneous infections (except meningitis):
50 to 75 mg/kg daily given in 2 divided doses every 12 hours. Total daily dose should not exceed 2 g.
Treatment of meningitis: Initial dose: 100 mg/kg (not to exceed 4 g). Thereafter, a total daily dose of 100 mg/kg/day (not to exceed 4 g) is recommended. The daily dose may be administered once a day (or in equally divided doses every 12 hours). The usual duration of therapy is 7 to 14 days.
For the prevention of secondary cases of meningococcal meningitis: A single intramuscular dose of 250 mg may be used for adults and 125 mg for children. longer therapy may be required.
For infections caused by Streptococcus pyogenes, therapy should be continued for at least 10 days. Or as prescribed by the physician. Usual duration of therapy is 4 to 14 days; In complicated infections,
Contraindications
Ceftriaxone is contraindicated in patients with known allergy to cephalosporin class of antibiotics.
Warning and Precautions
Modify dosage in patients with severe renal impairment; prolonged use may result in superinfection; use with caution in pateints with a history of penicillin allergy, especially lgE-mediated reactions; may cause antibiotic associated colitis or colitis secondary to C. difficile.
Pregnancy category B. No adequate and well-controlled studies in pregnant women. Ceftriaxone should be used in pregnancy only if clearly needed
Availability
RM Ceftriaxone 1G vial Box by 1’s
