RM VALSARTAN 160 MG

Angiotension II Receptor Blocker

Product Details

What is this medicine used for?

 

Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions

 

Treatment of heart failure (NYHA class II-IV); Valsartan significantly

reduced hospitalization for heart failure

 

Reduction of cardiovascular mortality in clinically stable patients with left ventricular failure or left ventricular dysfunction following

myocardial infarction 

 

How much and how often should you use this medicine?

The recommended starting dose of Valsartan is 80 mg or 160 mg once daily when used as monotherapy in patients who are not volume-depleted. Patients requiring greater reductions may be started at the higher dose. Valsartan may be used over a dose range of 80 mg to 320 mg daily, administered once a day.

 

The antihypertensive effect is substantially present within 2 weeks and maximal reduction is generally attained after 4 weeks. If additional antihypertensive effect is required over the starting dose range, the dose may be increased to a maximum of 320 mg or a diuretic may be added. Addition of a diuretic has a greater effect than dose increases beyond 80 mg.

 

Valsartan may be administered with other antihypertensive agents.

 

Contraindications

Biliary cirrhosis, cholestasis. Concomitant use with aliskiren in patient with diabetes mellitus or renal impairment (GFR<60 mL/min/1.73 m2). Severe hepatic impairment. Pregnancy.

 

Warning and Precautions

Fetal Toxicity

Valsartan can cause fetal harm when administered to a pregnant woman. Use of drugs that act on the renin angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Diovan as soon as possible

Hypotension

Excessive hypotension was rarely seen (0.1%) in patients with uncomplicated hypertension treated with Valsartan alone. In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur. This condition should be corrected prior to administration of Valsartan, or the treatment should start under close medical supervision.

 

Patients with heart failure or post-myocardial infarction patients given Valsartan commonly have some reduction in blood pressure, but discontinuation of therapy because of continuing symptomatic hypotension usually is not necessary when dosing instructions are followed. In controlled trials in heart failure patients, the incidence of hypotension in valsartan-treated patients was 5.5% compared to 1.8% in placebo-treated patients. In the Valsartan in Acute myocardial infarction trial (VALIANT), hypotension in post-myocardial infarction patients led to permanent discontinuation of therapy in 1.4% of valsartan-treated patients and 0.8% of captopril treated patients.

 

If excessive hypotension occurs, place the patient in the supine position and, if necessary, give intravenous normal saline. A transient hypotensive response is not a contraindication to further treatment, which usually can be continued without difficulty once the blood pressure has stabilized.

 

Impaired Renal Function

Changes in renal function including acute renal failure can be caused by drugs that inhibit the renin-angiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on Valsartan. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Valsartan

 

Availability

RM Valsartan 160 mg box of 30’s

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Php 995.00
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Php 8.00
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Php 160.00
RM ACICLOVIR 400 MG TAB

RM ACICLOVIR 400 MG TAB

Php 68.00
RM AMLODIPINE BESILATE 10 MG TAB

RM AMLODIPINE BESILATE 10 MG TAB

Php 9.00
RM GLICLAZIDE 80 MG TAB

RM GLICLAZIDE 80 MG TAB

Php 6.75
RM COTTON BUDS 108 TIPS

RM COTTON BUDS 108 TIPS

Php 22.75
RM FOLIC ACID 5 MG TAB

RM FOLIC ACID 5 MG TAB

Php 5.00
RM TRAVEL POUCH

RM TRAVEL POUCH

Php 123.50
RM ISOPROPYL 70% ALCOHOL 60 ML

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Php 22.50
RITEMED MUCOPID (REBAMIPIDE)

RITEMED MUCOPID (REBAMIPIDE)

Php 20.00
RM REMOSTON TAB 5+1

RM REMOSTON TAB 5+1

Php 35.00
RM ATORVASTATIN 10 MG TAB

RM ATORVASTATIN 10 MG TAB

Php 13.00
RM METOPROLOL TARTRATE 100 MG TAB

RM METOPROLOL TARTRATE 100 MG TAB

Php 4.90
RM OMEPRAZOLE 40 MG CAPSULE

RM OMEPRAZOLE 40 MG CAPSULE

Php 39.00
RM ETHYL ALCOHOL 70% 60 ML

RM ETHYL ALCOHOL 70% 60 ML

Php 22.00
RM FELODIPINE 5 MG TAB

RM FELODIPINE 5 MG TAB

Php 12.75
RM COLCHICINE 500 MCG

RM COLCHICINE 500 MCG

Php 4.35
RM ALLOPURINOL 100 MG TAB

RM ALLOPURINOL 100 MG TAB

Php 6.00
RM LOPERAMIDE CAP 9+1

RM LOPERAMIDE CAP 9+1

Php 5.50
RM DIPHENHYDRAMINE 50 MG CAP 100 BOX

RM DIPHENHYDRAMINE 50 MG CAP 100 BOX

Php 8.50
RM DOMPERIDONE TAB 9+1

RM DOMPERIDONE TAB 9+1

Php 13.50
RM GLUCOSAMINE 1.5 G

RM GLUCOSAMINE 1.5 G

Php 50.00
RM TERAZOSIN 5 MG

RM TERAZOSIN 5 MG

Php 32.14
RM SALBUTAMOL 2 MG TAB

RM SALBUTAMOL 2 MG TAB

Php 4.00
RM GLIBENCLAMIDE 5 MG

RM GLIBENCLAMIDE 5 MG

Php 5.80
RM ISOSORBIDE-5-MONONITRATE (ISMN) 60 MG

RM ISOSORBIDE-5-MONONITRATE (ISMN) 60 MG

Php 16.50
RM CEFUROXIME AXETIL 500 MG TAB

RM CEFUROXIME AXETIL 500 MG TAB

Php 52.75
RM TRI-V

RM TRI-V

Php 157.50
RM COTRIMOXAZOLE 200 MG SUSPENSION 60 ML

RM COTRIMOXAZOLE 200 MG SUSPENSION 60 ML

Php 84.00
RM CLOTRIMAZOLE 3 G

RM CLOTRIMAZOLE 3 G

Php 90.00
RM CETIRIZINE TAB 18+2

RM CETIRIZINE TAB 18+2

Php 342.00
RM FRUSEMA 20 MG TAB 100 BOX

RM FRUSEMA 20 MG TAB 100 BOX

Php 3.44
RM COTTON BALLS 50S

RM COTTON BALLS 50S

Php 22.50
RM TELMISARTAN + HTCZ 40 MG

RM TELMISARTAN + HTCZ 40 MG

Php 16.50
RM ISONIAZID + PYRIDOXINE HYDROCHLORIDE 200 MG/ 12 MG PER 5 ML SYRUP

RM ISONIAZID + PYRIDOXINE HYDROCHLORIDE 200 MG/ 12 MG PER 5 ML SYRUP

Php 50.00
RM NAPROXEN SODIUM 500 MG TAB

RM NAPROXEN SODIUM 500 MG TAB

Php 13.00
RM ASCORBIC+ZINC (ZINC-C<SUP>TM</SUP>) SYRUP 120 ML

RM ASCORBIC+ZINC (ZINC-CTM) SYRUP 120 ML

Php 106.00
RM PANTOPRAZOLE 40 MG

RM PANTOPRAZOLE 40 MG

Php 730.00
RM CARBOCISTEINE 500 MG

RM CARBOCISTEINE 500 MG

Php 6.50
RM DENGUETROL 25% 100 ML

RM DENGUETROL 25% 100 ML

Php 135.00
RM HEXETIDINE 120 ML

RM HEXETIDINE 120 ML

Php 148.00
RM IRBESARTAN 300 MG

RM IRBESARTAN 300 MG

Php 28.20
RM CARVEDILOL 25 MG TAB

RM CARVEDILOL 25 MG TAB

Php 8.04
RM CEFACLOR 125MG SUSPENSION 105 ML

RM CEFACLOR 125MG SUSPENSION 105 ML

Php 372.00
RM OLMESARTAN 20 MG TAB

RM OLMESARTAN 20 MG TAB

Php 32.00
RM WARMING OIL

RM WARMING OIL

Php 56.00
RM ROSUVASTATIN 20 MG

RM ROSUVASTATIN 20 MG

Php 33.75
RM DOMPERIDONE 10 MG TAB

RM DOMPERIDONE 10 MG TAB

Php 13.50
RM VERAPAMIL 240 MG TAB

RM VERAPAMIL 240 MG TAB

Php 42.50
RM ATENOLOL 100 MG TAB

RM ATENOLOL 100 MG TAB

Php 12.00
RM TERAZOSIN 2 MG

RM TERAZOSIN 2 MG

Php 26.79
RM METFORMIN 850 MG TAB

RM METFORMIN 850 MG TAB

Php 7.50
RM ALFUZOSIN HCI 10 MG TAB

RM ALFUZOSIN HCI 10 MG TAB

Php 46.00
RM GLIX 5 MG

RM GLIX 5 MG

Php 16.00
RM CLOXACILLIN 250 MG SOLUTION 60 ML

RM CLOXACILLIN 250 MG SOLUTION 60 ML

Php 230.00
RM PARAMAX (IBUPROFEN+PARACETAMOL)  32 5MG/200 MG TAB

RM PARAMAX (IBUPROFEN+PARACETAMOL) 32 5MG/200 MG TAB

Php 5.00
RM LOSARTAN + HYDROCHLOROTHIAZIDE (LOSARITE) 50 MG TAB

RM LOSARTAN + HYDROCHLOROTHIAZIDE (LOSARITE) 50 MG TAB

Php 13.25
PERIOKIN HYALURONIC SPRAY 40 ML

PERIOKIN HYALURONIC SPRAY 40 ML

Php 695.75
RM CEFALEXIN 250 MG SUSPENSION 60 ML

RM CEFALEXIN 250 MG SUSPENSION 60 ML

Php 186.00
RM SILDENAFIL 100 MG TAB

RM SILDENAFIL 100 MG TAB

Php 250.00
RM DICLOFENAC SODIUM 50 MG TAB

RM DICLOFENAC SODIUM 50 MG TAB

Php 16.00
RM PARACETAMOL 120 MG / 5 ML SYRUP

RM PARACETAMOL 120 MG / 5 ML SYRUP

Php 50.00
RM INSULYF R 100 IU/ML VIAL

RM INSULYF R 100 IU/ML VIAL

Php 700.00
RM CLINDAMYCIN 300 MG CAP

RM CLINDAMYCIN 300 MG CAP

Php 37.75
RM AMBROXOL 15 MG SYRUP 60 ML

RM AMBROXOL 15 MG SYRUP 60 ML

Php 72.00
RM ACICLOVIR 800 MG TAB

RM ACICLOVIR 800 MG TAB

Php 125.00
RM CO-AMOXICLAV 1 G TAB

RM CO-AMOXICLAV 1 G TAB

Php 58.75
RM MEROPENEM 1 G

RM MEROPENEM 1 G

Php 1,600.00
RM FRUSEMA 20 MG / 2 ML AMP 10 BOX

RM FRUSEMA 20 MG / 2 ML AMP 10 BOX

Php 58.04
RM AZITHROMYCIN 500 MG TAB

RM AZITHROMYCIN 500 MG TAB

Php 106.00
RM METFORMIN SR 500 MG TAB

RM METFORMIN SR 500 MG TAB

Php 6.25
RM ASCORBIC ACID 500 MG TAB

RM ASCORBIC ACID 500 MG TAB

Php 2.25
RM PARACETAMOL 125 MG SUPPOSITORY

RM PARACETAMOL 125 MG SUPPOSITORY

Php 9.50
RM TRAMADOL + PARACETAMOL

RM TRAMADOL + PARACETAMOL

Php 40.00