RM VALSARTAN 160 MG

Angiotension II Receptor Blocker

Product Details

What is this medicine used for?

 

Treatment of hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions

 

Treatment of heart failure (NYHA class II-IV); Valsartan significantly

reduced hospitalization for heart failure

 

Reduction of cardiovascular mortality in clinically stable patients with left ventricular failure or left ventricular dysfunction following

myocardial infarction 

 

How much and how often should you use this medicine?

The recommended starting dose of Valsartan is 80 mg or 160 mg once daily when used as monotherapy in patients who are not volume-depleted. Patients requiring greater reductions may be started at the higher dose. Valsartan may be used over a dose range of 80 mg to 320 mg daily, administered once a day.

 

The antihypertensive effect is substantially present within 2 weeks and maximal reduction is generally attained after 4 weeks. If additional antihypertensive effect is required over the starting dose range, the dose may be increased to a maximum of 320 mg or a diuretic may be added. Addition of a diuretic has a greater effect than dose increases beyond 80 mg.

 

Valsartan may be administered with other antihypertensive agents.

 

Contraindications

Biliary cirrhosis, cholestasis. Concomitant use with aliskiren in patient with diabetes mellitus or renal impairment (GFR<60 mL/min/1.73 m2). Severe hepatic impairment. Pregnancy.

 

Warning and Precautions

Fetal Toxicity

Valsartan can cause fetal harm when administered to a pregnant woman. Use of drugs that act on the renin angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Diovan as soon as possible

Hypotension

Excessive hypotension was rarely seen (0.1%) in patients with uncomplicated hypertension treated with Valsartan alone. In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur. This condition should be corrected prior to administration of Valsartan, or the treatment should start under close medical supervision.

 

Patients with heart failure or post-myocardial infarction patients given Valsartan commonly have some reduction in blood pressure, but discontinuation of therapy because of continuing symptomatic hypotension usually is not necessary when dosing instructions are followed. In controlled trials in heart failure patients, the incidence of hypotension in valsartan-treated patients was 5.5% compared to 1.8% in placebo-treated patients. In the Valsartan in Acute myocardial infarction trial (VALIANT), hypotension in post-myocardial infarction patients led to permanent discontinuation of therapy in 1.4% of valsartan-treated patients and 0.8% of captopril treated patients.

 

If excessive hypotension occurs, place the patient in the supine position and, if necessary, give intravenous normal saline. A transient hypotensive response is not a contraindication to further treatment, which usually can be continued without difficulty once the blood pressure has stabilized.

 

Impaired Renal Function

Changes in renal function including acute renal failure can be caused by drugs that inhibit the renin-angiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on Valsartan. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Valsartan

 

Availability

RM Valsartan 160 mg box of 30’s

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RM NAPROXEN SODIUM 500 MG TAB

Php 13.00
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Php 16.00
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Php 58.04
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Php 6.00
RM IRBESARTAN 150 MG

RM IRBESARTAN 150 MG

Php 17.20
RM ASCORBIC ACID 500 MG TAB

RM ASCORBIC ACID 500 MG TAB

Php 2.25
RM TRI-V

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Php 157.50
RM COTTON BUDS 108 TIPS

RM COTTON BUDS 108 TIPS

Php 22.75
RM PREGABALIN 150 MG CAP 56

RM PREGABALIN 150 MG CAP 56

Php 52.90
RM RELAXING OIL

RM RELAXING OIL

Php 56.00
RM BETAMETHASONE DIPROPIONATE 500 MCG/ G CREAM

RM BETAMETHASONE DIPROPIONATE 500 MCG/ G CREAM

Php 245.00
RM CEFTRIAXONE 1 G VIAL

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Php 863.20
RM TERAZOSIN 5 MG

RM TERAZOSIN 5 MG

Php 32.14
RM PANTOPRAZOLE 40 MG

RM PANTOPRAZOLE 40 MG

Php 730.00
RM OMEPRAZOLE 40 MG VIALS 1 BOX

RM OMEPRAZOLE 40 MG VIALS 1 BOX

Php 600.00
RM ATORVASTATIN 40 MG TAB

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Php 22.75
RM CEFEPIME 1 G POWDER

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Php 1,400.00
RM DENGUETROL 25% 100 ML

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Php 135.00
RM AMOXICILLIN 125 MG SUSPENSION 60 ML

RM AMOXICILLIN 125 MG SUSPENSION 60 ML

Php 77.00
RM COTRIMOXAZOLE 400 MG TAB

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Php 6.75
RM DIPHENHYDRAMINE 12.5 MG ELIXIR 60 ML

RM DIPHENHYDRAMINE 12.5 MG ELIXIR 60 ML

Php 80.00
RM PARAMAX TAB 9+1

RM PARAMAX TAB 9+1

Php 45.00
RM ISONIAZID + PYRIDOXINE HYDROCHLORIDE 200 MG/ 12 MG PER 5 ML SYRUP

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Php 50.00
RM CEFACLOR 250 MG SUSPENSION 30 ML

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RM NEUTRACID TAB 9+1 (ALUMINUM HYDROXIDE + MAGNESIUM HYDROXIDE)

Php 3.00
RM POVIDONE IODINE 10% SOL 30 ML

RM POVIDONE IODINE 10% SOL 30 ML

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RM CETIRIZINE 5 MG SYRUP 60 ML

RM CETIRIZINE 5 MG SYRUP 60 ML

Php 200.00
RM OLMESARTAN 20 MG TAB

RM OLMESARTAN 20 MG TAB

Php 32.00
RITEMED COLD RUB

RITEMED COLD RUB

Php 116.00
RM PARACETAMOL 120 MG / 5 ML SYRUP

RM PARACETAMOL 120 MG / 5 ML SYRUP

Php 50.00
RM LOSAR+AMLO 50/5MG

RM LOSAR+AMLO 50/5MG

Php 20.00
RM CARBOCISTEINE 500 MG

RM CARBOCISTEINE 500 MG

Php 6.50
RM ISOPROPYL 70% ALCOHOL 60 ML

RM ISOPROPYL 70% ALCOHOL 60 ML

Php 22.50
RM CELECOXIB 200 MG CAP

RM CELECOXIB 200 MG CAP

Php 23.50
RM FIBERMATE ORANGE FLAVOR

RM FIBERMATE ORANGE FLAVOR

Php 20.75
RM CLONIDINE HCL 150 MCG TAB

RM CLONIDINE HCL 150 MCG TAB

Php 26.00
RM LORATADINE 10 MG TAB

RM LORATADINE 10 MG TAB

Php 19.00
RM ACICLOVIR 400 MG TAB

RM ACICLOVIR 400 MG TAB

Php 68.00
RM ENALAPRIL 20 MG

RM ENALAPRIL 20 MG

Php 16.00
RM CETIRIZINE 10 MG TAB

RM CETIRIZINE 10 MG TAB

Php 16.00
RM IBUPROFEN 200 MG SOFTGEL CAPSULE

RM IBUPROFEN 200 MG SOFTGEL CAPSULE

Php 4.50
RM CEFUROXIME AXETIL 500 MG TAB

RM CEFUROXIME AXETIL 500 MG TAB

Php 52.75
RM METRONIDAZOLE 10 MG/ G GEL

RM METRONIDAZOLE 10 MG/ G GEL

Php 328.00
RM COTRIMOXAZOLE 800 MG TAB

RM COTRIMOXAZOLE 800 MG TAB

Php 12.00
RM PETROLEUM JELLY

RM PETROLEUM JELLY

Php 45.00
RM DEXTROMETHORPHAN 10 MG SYRUP 60 ML

RM DEXTROMETHORPHAN 10 MG SYRUP 60 ML

Php 60.00
RM INSULYF N 100 IU/ML VIAL

RM INSULYF N 100 IU/ML VIAL

Php 700.00
RM TERBINAFINE 10 MG/G 15 G CREAM

RM TERBINAFINE 10 MG/G 15 G CREAM

Php 300.00
RM DICYCLOVERINE 10 MG TABLET

RM DICYCLOVERINE 10 MG TABLET

Php 10.00
RM FOLIC ACID 5 MG TAB

RM FOLIC ACID 5 MG TAB

Php 5.00
RM OMEPRAZOLE 20 MG TAB

RM OMEPRAZOLE 20 MG TAB

Php 27.00
RM ETHYL ALCOHOL 70% 60 ML

RM ETHYL ALCOHOL 70% 60 ML

Php 22.00
RM LOSARTAN + HYDROCHLOROTHIAZIDE (LOSARITE) 100 MG TAB

RM LOSARTAN + HYDROCHLOROTHIAZIDE (LOSARITE) 100 MG TAB

Php 16.25
RM TRAVEL POUCH

RM TRAVEL POUCH

Php 123.50
RM AMBROXOL 30 MG TAB

RM AMBROXOL 30 MG TAB

Php 8.00
RM AMLODIPINE BESILATE 5 MG TAB

RM AMLODIPINE BESILATE 5 MG TAB

Php 6.47
RM CEFUROXIME AXETIL 250 MG TAB

RM CEFUROXIME AXETIL 250 MG TAB

Php 31.00
RM LOSARTAN 50 MG TAB

RM LOSARTAN 50 MG TAB

Php 12.86
RM ALLOPURINOL 100 MG TAB

RM ALLOPURINOL 100 MG TAB

Php 6.00
RM MEFENAMIC ACID 250 MG TAB

RM MEFENAMIC ACID 250 MG TAB

Php 3.75
RM LINEZOLID 2 MG SOL 1 BAG

RM LINEZOLID 2 MG SOL 1 BAG

Php 4,144.00
RM CLONIDINE HCL 75 MCG TAB

RM CLONIDINE HCL 75 MCG TAB

Php 17.00
RM SALBUTAMOL 2 MG SYR 60 ML

RM SALBUTAMOL 2 MG SYR 60 ML

Php 2.75
RM BROMHEXINE 8 MG TAB

RM BROMHEXINE 8 MG TAB

Php 4.00