RM CLARITHROMYCIN 500 MG TAB

Antibacterial

Product Details

What is this medicine used for?

·         For the treatment of the following infections caused by susceptible microorganisms:

  • Upper respiratory tract infections including streptococcal pharyngitis and  tonsillitis
  • Acute otitis media and acute maxillary sinusitis
  • Lower respiratory tract infections including atypical pneumonia, bronchitis
  • Skin and skin structure infections including impetigo, folliculitis, cellulitis, abscesses (abscesses usually require surgical drainage)
  • Disseminated or localized mycobacterial infections due to Mycobacterium intracellulare or Mycobacterium avium. Localized infections due to Mycobacterium kansasii, Mycobacterium chelonae and Mycobacterium fortuitum (usually in combination with other antimicrobial agents)
  • Helicobacter pylori infections (in combination with other drugs)

Odontogenic infections

How much and how often should you use this medicine?

Clarithromycin tablets and suspension may be given with or without food. Clarithromycin suspension may be given with milk.

 

INDICATIONS

  

RECOMMENDED ORAL ADULT DOSE

  

RECOMMENDED ORAL

 

PEDIATRIC DOSE
 

 Non-Mycobacterial Infections

 

 

  

Usual adult dose: 250 to 500 mg every 12 hours for 7 to 14 days, depending on the type and severity of infection.

  

Usual pediatric dose: 15 mg/kg body weight/day to be given in two divided doses every 12 hours for 5 to 10 days depending on the type and severity of infection.

 
 

Age Group

  

Recommended Dose every

 

12 hours
 

6 months to 1 year

  

2.5 mL

 

(1/2 teaspoonful)
 

2 to 6 years

  

5 mL

 

(1 teaspoonful)
 

7 to 12 years

  

7.5 to 10 mL

 

(1 ½ to

 

2 teaspoonsful)
 

 
 

 Disseminated or Localized Mycobacterial Infections

 

 

  

500 mg every 12 hours.

 

Treatment should be continued for as long as clinical improvement is observed.

 

Concomitant treatment with other anti- mycobacterial drugs may be beneficial.

  

15 to 30 mg/kg body weight/day to be given in two divided doses every           12 hours (up to a maximum of 500 mg every 12 hours).

 

Treatment should be continued for as long as clinical improvement is observed.

 

Concomitant treatment with other anti-mycobacterial drugs may be beneficial.

 

 

Prophylaxis of Mycobacterium avium complex (MAC) Infections in HIV+/AIDS patients

  

500 mg every 12 hours.

 

Treatment should be continued while CD4 count is less than 100/mm3.

  

15 mg/kg body weight/day to be given in two divided doses (up to a maximum of       500 mg every 12 hours).

 

Treatment should be continued while CD4 count is less than 100/mm3.
 

Treatment of MAC Infections in HIV+/AIDS patients

 

 

  

500 mg every 12 hours.

 

Treatment should be continued for as long as   clinical improvement is observed.

 

Clarithromycin should be used in combination with other antimycobacterial drugs with activity against MAC, such as ethambutol, rifabutin and rifampicin.

  

15 to 30 mg/kg body weight/day to be given in two divided doses (up to a maximum of 500 mg every 12 hours).

 

Treatment should be continued for as long as clinical improvement is observed.

 

Clarithromycin should be used in combination with other antimycobacterial drugs with activity against MAC, such as ethambutol, rifabutin and rifampicin.
 

 Helicobacter pylori infections

 

 

  

Triple therapy regimens:

Clarithromycin 500 mg plus amoxicillin 1000 mg plus omeprazole 20 mg, all twice daily for 7 to 10 days, OR

 

Clarithromycin 500 mg plus amoxicillin 1000 mg plus pantoprazole 40 mg, all twice daily for one week

 

 

 

Dual therapy regimen:

 

Clarithromycin 500 mg three times daily plus omeprazole 40 mg once daily for

 

14 days, followed by omeprazole 20 mg or

 

40 mg once daily for an additional 14 days.

  

 

 

--
 

Odontogenic infections

  

250 mg every 12 hours

 

for 5 days

  

--
 

Or, as prescribed by a physician.

 

Contraindications

  • Hypersensitivity to Clarithromycin or any ingredient in the product
  • Cisapride, Pimozide, Astamizole, Tefernadine, Ergotamine, Dihydroergotamine: risk of arrhythmia (abnormal heart rhythm)
  • Warfarin: increased risk of bleeding
  • Carbamazepine: drowsiness, dizziness
  • Colchicine:  may cause nausea, vomiting, abdominal pain
  • Ciclosporin: increased risk of kidney toxicity
  • Digoxin: increase risk of digoxin toxicity
  • Atorvastatin, Simvastatin: muscle pain and weakness
  • Triazolam: increased risk of drowsiness and confusion

 

Availability

  • Clarithromycin 500 mg Tablet - Boxes of 50’s (in blister pack by 10’s)

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RM LEVOFLOXACIN 500 MG TAB

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RM CEFTRIAXONE 1 G VIAL

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RM DIPHENHYDRAMINE 50 MG CAP 100 BOX

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RM GLIX 5 MG

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RM METFORMIN 850 MG TAB

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RM SIMVASTATIN 20 MG TAB

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RM AMBROXOL 30 MG SYRUP 120 ML

RM AMBROXOL 30 MG SYRUP 120 ML

Php 150.00
RM CINNARIZINE 25 MG TAB VERZIRON

RM CINNARIZINE 25 MG TAB VERZIRON

Php 36.00
RM ZELEXIN 250 MG CAP

RM ZELEXIN 250 MG CAP

Php 14.50
RM ATORVASTATIN 40 MG TAB

RM ATORVASTATIN 40 MG TAB

Php 22.75
RM ASCORBIC ACID 500 MG TAB

RM ASCORBIC ACID 500 MG TAB

Php 2.25
RM AMOXICILLIN 125 MG SUSPENSION 60 ML

RM AMOXICILLIN 125 MG SUSPENSION 60 ML

Php 77.00
RM CEFALEXIN 250 MG SUSPENSION 60 ML

RM CEFALEXIN 250 MG SUSPENSION 60 ML

Php 186.00
RM MEROPENEM 500 MG

RM MEROPENEM 500 MG

Php 950.00
RM IRBESARTAN 300 MG

RM IRBESARTAN 300 MG

Php 28.20
RM MUPIROCIN 5 G TUBE OIN 1 BOX

RM MUPIROCIN 5 G TUBE OIN 1 BOX

Php 225.00
RM LOSARTAN + HYDROCHLOROTHIAZIDE (LOSARITE) 50 MG TAB

RM LOSARTAN + HYDROCHLOROTHIAZIDE (LOSARITE) 50 MG TAB

Php 13.25
RM FRUSEMA 40 MG TAB 100 BOX

RM FRUSEMA 40 MG TAB 100 BOX

Php 5.20
RM NEUTRACID 9+1 BS PH (PACK)

RM NEUTRACID 9+1 BS PH (PACK)

Php 3.00
RM HEXETIDINE 120 ML

RM HEXETIDINE 120 ML

Php 148.00
RM CLOTRIMAZOLE 3 G

RM CLOTRIMAZOLE 3 G

Php 90.00
RM PARACETAMOL 250 MG SYRUP 60 ML

RM PARACETAMOL 250 MG SYRUP 60 ML

Php 75.00
RM HEXETIDINE 60 ML

RM HEXETIDINE 60 ML

Php 89.00
RM OMEPRAZOLE TAB 9+1

RM OMEPRAZOLE TAB 9+1

Php 21.00
RM POVIDONE IODINE 10% SOL 60 ML

RM POVIDONE IODINE 10% SOL 60 ML

Php 90.00
KIN WHITENING 75 ML

KIN WHITENING 75 ML

Php 262.56
RM VALSARTAN 80 MG

RM VALSARTAN 80 MG

Php 17.86
RITEMED COLD RUB

RITEMED COLD RUB

Php 116.00
RM TERAZOSIN 2 MG

RM TERAZOSIN 2 MG

Php 26.79
RM LORATADINE 10 MG TAB

RM LORATADINE 10 MG TAB

Php 19.00
RM BISACODYL 5 MG SUPPOSITORY (CONLAX-5)

RM BISACODYL 5 MG SUPPOSITORY (CONLAX-5)

Php 39.00
RM AMBROXOL 30 MG SYRUP 60 ML

RM AMBROXOL 30 MG SYRUP 60 ML

Php 80.00
RM BISACODYL 5 MG TAB

RM BISACODYL 5 MG TAB

Php 15.00
RM CO-AMOXICLAV 625 MG TAB

RM CO-AMOXICLAV 625 MG TAB

Php 36.75
RM ACICLOVIR 800 MG TAB

RM ACICLOVIR 800 MG TAB

Php 125.00
RM BOMAX + D (ALENDRONIC ACID + VITAMIN D3) 70 MG / 2800 IU TAB

RM BOMAX + D (ALENDRONIC ACID + VITAMIN D3) 70 MG / 2800 IU TAB

Php 300.00
RM MELOXICAM 15 MG TAB

RM MELOXICAM 15 MG TAB

Php 43.50
RM FELODIPINE 5 MG TAB

RM FELODIPINE 5 MG TAB

Php 12.75
RM PARAMAX (IBUPROFEN+PARACETAMOL) 32 5MG/200 MG TAB

RM PARAMAX (IBUPROFEN+PARACETAMOL) 32 5MG/200 MG TAB

Php 5.00
RM VERAPAMIL 240 MG TAB

RM VERAPAMIL 240 MG TAB

Php 42.50
RM PREGABALIN 150 MG CAP 56

RM PREGABALIN 150 MG CAP 56

Php 52.90
RM FRUSEMA 20 MG TAB 100 BOX

RM FRUSEMA 20 MG TAB 100 BOX

Php 3.44
RM MELOXICAM 7.5 MG TAB

RM MELOXICAM 7.5 MG TAB

Php 29.00
RM CEFUROXIME 150 MG VIAL

RM CEFUROXIME 150 MG VIAL

Php 242.86
KIN GINGIVAL COMPLEX MOUTHWASH 250 ML

KIN GINGIVAL COMPLEX MOUTHWASH 250 ML

Php 623.15
RM GLUCOSAMINE 1.5 G

RM GLUCOSAMINE 1.5 G

Php 50.00
RM DOMPERIDONE TAB 9+1

RM DOMPERIDONE TAB 9+1

Php 13.50
RM ISOPROPYL 70% ALCOHOL 60 ML

RM ISOPROPYL 70% ALCOHOL 60 ML

Php 22.50
RM NAPROXEN SODIUM 500 MG TAB

RM NAPROXEN SODIUM 500 MG TAB

Php 13.00
RM AMOXICILLIN 250 MG CAP

RM AMOXICILLIN 250 MG CAP

Php 5.50
RM VALSARTAN 160 MG

RM VALSARTAN 160 MG

Php 25.00
RM IRON+FOLIC TAB

RM IRON+FOLIC TAB

Php 4.00
RM CLOPIDOGREL 75 MG TAB

RM CLOPIDOGREL 75 MG TAB

Php 20.50
RM ETHYL ACLHOCOL

RM ETHYL ACLHOCOL

Php 580.00
RM CEFEPIME 2G POWDER

RM CEFEPIME 2G POWDER

Php 2,700.00