RM CLARITHROMYCIN 500 MG TAB

Antibacterial

Product Details

What is this medicine used for?

·         For the treatment of the following infections caused by susceptible microorganisms:

  • Upper respiratory tract infections including streptococcal pharyngitis and  tonsillitis
  • Acute otitis media and acute maxillary sinusitis
  • Lower respiratory tract infections including atypical pneumonia, bronchitis
  • Skin and skin structure infections including impetigo, folliculitis, cellulitis, abscesses (abscesses usually require surgical drainage)
  • Disseminated or localized mycobacterial infections due to Mycobacterium intracellulare or Mycobacterium avium. Localized infections due to Mycobacterium kansasii, Mycobacterium chelonae and Mycobacterium fortuitum (usually in combination with other antimicrobial agents)
  • Helicobacter pylori infections (in combination with other drugs)

Odontogenic infections

How much and how often should you use this medicine?

Clarithromycin tablets and suspension may be given with or without food. Clarithromycin suspension may be given with milk.

 

INDICATIONS

  

RECOMMENDED ORAL ADULT DOSE

  

RECOMMENDED ORAL

 

PEDIATRIC DOSE
 

 Non-Mycobacterial Infections

 

 

  

Usual adult dose: 250 to 500 mg every 12 hours for 7 to 14 days, depending on the type and severity of infection.

  

Usual pediatric dose: 15 mg/kg body weight/day to be given in two divided doses every 12 hours for 5 to 10 days depending on the type and severity of infection.

 
 

Age Group

  

Recommended Dose every

 

12 hours
 

6 months to 1 year

  

2.5 mL

 

(1/2 teaspoonful)
 

2 to 6 years

  

5 mL

 

(1 teaspoonful)
 

7 to 12 years

  

7.5 to 10 mL

 

(1 ½ to

 

2 teaspoonsful)
 

 
 

 Disseminated or Localized Mycobacterial Infections

 

 

  

500 mg every 12 hours.

 

Treatment should be continued for as long as clinical improvement is observed.

 

Concomitant treatment with other anti- mycobacterial drugs may be beneficial.

  

15 to 30 mg/kg body weight/day to be given in two divided doses every           12 hours (up to a maximum of 500 mg every 12 hours).

 

Treatment should be continued for as long as clinical improvement is observed.

 

Concomitant treatment with other anti-mycobacterial drugs may be beneficial.

 

 

Prophylaxis of Mycobacterium avium complex (MAC) Infections in HIV+/AIDS patients

  

500 mg every 12 hours.

 

Treatment should be continued while CD4 count is less than 100/mm3.

  

15 mg/kg body weight/day to be given in two divided doses (up to a maximum of       500 mg every 12 hours).

 

Treatment should be continued while CD4 count is less than 100/mm3.
 

Treatment of MAC Infections in HIV+/AIDS patients

 

 

  

500 mg every 12 hours.

 

Treatment should be continued for as long as   clinical improvement is observed.

 

Clarithromycin should be used in combination with other antimycobacterial drugs with activity against MAC, such as ethambutol, rifabutin and rifampicin.

  

15 to 30 mg/kg body weight/day to be given in two divided doses (up to a maximum of 500 mg every 12 hours).

 

Treatment should be continued for as long as clinical improvement is observed.

 

Clarithromycin should be used in combination with other antimycobacterial drugs with activity against MAC, such as ethambutol, rifabutin and rifampicin.
 

 Helicobacter pylori infections

 

 

  

Triple therapy regimens:

Clarithromycin 500 mg plus amoxicillin 1000 mg plus omeprazole 20 mg, all twice daily for 7 to 10 days, OR

 

Clarithromycin 500 mg plus amoxicillin 1000 mg plus pantoprazole 40 mg, all twice daily for one week

 

 

 

Dual therapy regimen:

 

Clarithromycin 500 mg three times daily plus omeprazole 40 mg once daily for

 

14 days, followed by omeprazole 20 mg or

 

40 mg once daily for an additional 14 days.

  

 

 

--
 

Odontogenic infections

  

250 mg every 12 hours

 

for 5 days

  

--
 

Or, as prescribed by a physician.

 

Contraindications

  • Hypersensitivity to Clarithromycin or any ingredient in the product
  • Cisapride, Pimozide, Astamizole, Tefernadine, Ergotamine, Dihydroergotamine: risk of arrhythmia (abnormal heart rhythm)
  • Warfarin: increased risk of bleeding
  • Carbamazepine: drowsiness, dizziness
  • Colchicine:  may cause nausea, vomiting, abdominal pain
  • Ciclosporin: increased risk of kidney toxicity
  • Digoxin: increase risk of digoxin toxicity
  • Atorvastatin, Simvastatin: muscle pain and weakness
  • Triazolam: increased risk of drowsiness and confusion

 

Availability

  • Clarithromycin 500 mg Tablet - Boxes of 50’s (in blister pack by 10’s)

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RM TERAZOSIN 2 MG

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RM ALLOPURINOL 300 MG TAB

RM ALLOPURINOL 300 MG TAB

Php 13.00
RM ALLOPURINOL 100 MG TAB

RM ALLOPURINOL 100 MG TAB

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RM MOMETASONE 1 MG/ G (0.1% W/W) 5 G CREAM

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RM LORATADINE TAB 9+1

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RM AZITHROMYCIN 500 MG TAB

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RM ATORVASTATIN 20 MG TAB

RM ATORVASTATIN 20 MG TAB

Php 16.50
RM AMBROXOL 15 MG SYRUP 120 ML

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PERIOKIN HYALURONIC 1% MOUTH GEL 30 G

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RM HYOSCINE N-BUTYLBROMIDE 10 MG TAB

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RM GLIX 5 MG

RM GLIX 5 MG

Php 16.00
RM ATORVASTATIN 40 MG TAB

RM ATORVASTATIN 40 MG TAB

Php 22.75
RM ROSUVASTATIN 20 MG

RM ROSUVASTATIN 20 MG

Php 33.75
RM LOPERAMIDE CAP 9+1

RM LOPERAMIDE CAP 9+1

Php 5.50
RM CETIRIZINE 5 MG SYRUP 60 ML

RM CETIRIZINE 5 MG SYRUP 60 ML

Php 200.00
RM CLOXACILLIN 250 MG SOLUTION 60 ML

RM CLOXACILLIN 250 MG SOLUTION 60 ML

Php 230.00
RM CLONIDINE HCL 150 MCG TAB

RM CLONIDINE HCL 150 MCG TAB

Php 26.00
RM CEFEPIME 2G POWDER

RM CEFEPIME 2G POWDER

Php 2,700.00
RM BROMHEXINE 8 MG TAB

RM BROMHEXINE 8 MG TAB

Php 4.00
RM OMEPRAZOLE 20 MG TAB

RM OMEPRAZOLE 20 MG TAB

Php 27.00
RM OMEPRAZOLE 40 MG VIALS 1 BOX

RM OMEPRAZOLE 40 MG VIALS 1 BOX

Php 600.00
RM IRBESARTAN 300 MG

RM IRBESARTAN 300 MG

Php 28.20
RM BOMAX + D (ALENDRONIC ACID + VITAMIN D3) 70 MG / 2800 IU TAB

RM BOMAX + D (ALENDRONIC ACID + VITAMIN D3) 70 MG / 2800 IU TAB

Php 262.50
RM ACICLOVIR 400 MG TAB

RM ACICLOVIR 400 MG TAB

Php 68.00
RM MELOXICAM 7.5 MG TAB

RM MELOXICAM 7.5 MG TAB

Php 29.00
RM CLOPIDOGREL 75 MG TAB

RM CLOPIDOGREL 75 MG TAB

Php 23.00
RM CHLORPHENAMINE 5 MG TAB 100 BOX

RM CHLORPHENAMINE 5 MG TAB 100 BOX

Php 4.00
RM MEROPENEM 1 G

RM MEROPENEM 1 G

Php 1,600.00
RM COTRIMOXAZOLE 200 MG SUSPENSION 60 ML

RM COTRIMOXAZOLE 200 MG SUSPENSION 60 ML

Php 84.00
RM LAGUNDI SYRUP 120 ML

RM LAGUNDI SYRUP 120 ML

Php 130.00
RITEMED COLD RUB

RITEMED COLD RUB

Php 116.00
RM OMEPRAZOLE TAB 9+1

RM OMEPRAZOLE TAB 9+1

Php 21.00
RM ISOPROPYL 70% ALCOHOL 250ML

RM ISOPROPYL 70% ALCOHOL 250ML

Php 50.00
RM CEFACLOR 125 MG SUSPENSION 30 ML

RM CEFACLOR 125 MG SUSPENSION 30 ML

Php 150.00
RM RELAXING OIL

RM RELAXING OIL

Php 56.00
RM DOMPERIDONE 10 MG TAB

RM DOMPERIDONE 10 MG TAB

Php 13.50
RM METOPROLOL TARTRATE 50 MG TAB

RM METOPROLOL TARTRATE 50 MG TAB

Php 3.00
RM DICYCLOVERINE 10 MG SYRUP 60 ML

RM DICYCLOVERINE 10 MG SYRUP 60 ML

Php 80.00
RM VALSARTAN 80 MG

RM VALSARTAN 80 MG

Php 17.86
RM FRUSEMA 20 MG / 2 ML AMP 10 BOX

RM FRUSEMA 20 MG / 2 ML AMP 10 BOX

Php 58.04
RM ISOSORBIDE-5-MONONITRATE (ISMN) 60 MG

RM ISOSORBIDE-5-MONONITRATE (ISMN) 60 MG

Php 16.50
RM SOD ASCORBATE BS PH

RM SOD ASCORBATE BS PH

Php 450.00
RM CEFUROXIME 150 MG VIAL

RM CEFUROXIME 150 MG VIAL

Php 242.86
RM ZELEXIN 500 MG CAP

RM ZELEXIN 500 MG CAP

Php 20.50
RM LORATADINE 10 MG TAB

RM LORATADINE 10 MG TAB

Php 19.00
RM PARACETAMOL 500 MG TAB

RM PARACETAMOL 500 MG TAB

Php 2.75
RM WARMING OIL

RM WARMING OIL

Php 56.00
RM CEFACLOR 250 MG SUSPENSION 105 ML

RM CEFACLOR 250 MG SUSPENSION 105 ML

Php 630.00
RM ASCORBIC ACID 500 MG TAB

RM ASCORBIC ACID 500 MG TAB

Php 2.25
RM LAGUNDI 5+1 BS PH (PACK)

RM LAGUNDI 5+1 BS PH (PACK)

Php 25.00
RM PARAMAX 9+1 BS PH (PACK)

RM PARAMAX 9+1 BS PH (PACK)

Php 45.00
RM AMBROXOL 30 MG SYRUP 120 ML

RM AMBROXOL 30 MG SYRUP 120 ML

Php 150.00
RM CINNARIZINE 25 MG TAB VERZIRON

RM CINNARIZINE 25 MG TAB VERZIRON

Php 36.00
RM SIMVASTATIN 20 MG TAB

RM SIMVASTATIN 20 MG TAB

Php 18.00
RM ASCORBIC ACID 100 MG SYRUP 120 ML

RM ASCORBIC ACID 100 MG SYRUP 120 ML

Php 95.00
RM HEXETIDINE 60 ML

RM HEXETIDINE 60 ML

Php 89.00
RM CARVEDILOL 25 MG TAB

RM CARVEDILOL 25 MG TAB

Php 8.04
RM FRUSEMA 20 MG TAB 100 BOX

RM FRUSEMA 20 MG TAB 100 BOX

Php 3.44
RM CEFACLOR 125MG SUSPENSION 105 ML

RM CEFACLOR 125MG SUSPENSION 105 ML

Php 372.00