What is this medicine used for?
- As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.
- Metformin maybe used as monotherapy or in combination with other oral antidiabetic agents or with insulin.
How much and how often should you use this medicine?
150mg to 300mg once daily. The usual recommended initial and maintenance dose is 150mg once daily.
In hypertensive type 2 diabetic patients: 150mg-300mg once daily or as prescribed by the physician.
- Hypersensitivity to Merformin HCI or to any ingredient in the product
- Unstable and/or type 1 (insulin-dependent) diabetes mellitus
- History of lactic acidosis irrespective of precipitating factors
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma. Treat diabetic ketoacidosis with insulin.
- Severe renal impairment (eGFR <30mL/min/1.73m2)
- Acute conditions with the potential to alter renal function such as
- Dehydration due to persistent or severe diarrhea, recurring vomiting
- Severe infection
- Diagnostic examinations (e.g. intravenous, urography, angiography) that would involve the use of iodinated contrast agents/media.
- Acute or chronic disease which may cause tissue hypoxia such as
- Cardiac or respiratory failure
- Recent myocardial infraction
- Acute or chronic alcoholism
- Severe liver disease
- Pregnancy or breast feeding
Warnings and Precautions
- Lactic Acidosis
- Monitoring Renal Function
- Macro Vascular Outcomes
- Radiological Studies
- Hyoxic States
- Impared Hepatic Function
- Vitamin B Levels
- Maintaining Adequate Glycemic Control during period of stress
- Effects on Ability to Drive and use Machines
AvailabilityWarnings and Precautions
Metformin SR 500mg- Box of 100’s (in Blister Pack by 10’s)