What is this medicine used for?
Treatment of functional conditions involving smooth muscle spasm of the GI tract (e.g., mucus colitis, spastic colon and irritable bowel syndrome)
How much and how often should you use this medicine?
Orally, 3 times a day, as needed
Syrup: Children 2 to 12 years old: 5 mL (1 teaspoonful)
Infants 6 months to < 2 years old: 2.5 to 5 mL (1/2 to 1 teaspoonful); NOT to exceed 20 mL (40 mg) a day; administer 15 minutes before feeding; may be diluted immediately prior to use with water if needed
Hypersensitivity to dicycloverine or other ingredients in the product, Infants less than 6 months old, Breastfeeding women, Patients with the following conditions: Unstable cardiovascular status in acute hemorrhage, Myasthenia gravis, Glaucoma, Obstructive uropathy, Obstructive disease of the GI tract, Paralytic ileus and intestinal atony, Severe ulcerative colitis, Reflux esophagitis
Warnings and Precautions:
There are published cases reporting that the administration of dicycloverine hydrochloride syrup to infants (3
months old) has been followed by serious respiratory symptoms (dyspnea, shortness of breath, breathlessness,
respiratory collapse, apnea and asphyxia), seizures, syncope, pulse rate fluctuations, muscular hypotonia,
coma, and death.
Adverse effects with dicycloverine are usually related to its pharmacological actions of inhibiting muscarinic receptors, including dry mouth, dizziness, blurred vision, nausea, light-headedness, somnolence, asthenia, and nervousness. These effects are dose-related and are usually reversible when treatment is discontinued.
Interaction w/ other medicaments:
Antacids, Anticholinergics: Increased anticholinergic effects of these agents, including amantadine, Class I antiarrhythic agents (e.g., quinidine), antihistamines, antipsychotic agents (e.g., phenothiazines), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, etc.Antiglaucoma Agents: Antagonize the effects of antiglaucoma agents; antichlolinergics in increased intraocular pressure may be hazardous when given with corticosteroids