What is this medicine used for?
- It is used as adjunct to proper dietary management, physical exercise and weight reduction to improve glycemic control in adults with type 2 diabetes mellitus whose hyperglycemia cannot be controlled by diet and exercise alone and may be used as monotherapy or in combination with metformin or insulin.
How much and how often should you use this medicine?
Usual Starting Dose: 1 mg once a day with breakfast or the first main meal
Start patients who may be more sensitive to hypoglycemic agents at 1 mg once a day and titrate dose carefully
No exact dosage relationship exists between glimepiride and other oral hypoglycemic agents.
Maximum Starting Dose: Not more than 2 mg once a day
Failure to follow an appropriate drug regimen may precipitate hypoglycemia. Patients who do not adhere to their prescribed dietary and drug regimen are more prone to exhibit unsatisfactory response to therapy.
Usual Maintenance Dose: 1 to 4 mg once a day
Maximum Recommended Dose: 8 mg once a day
After reaching a dose of 2 mg, any increase in dosage should be in increments of not more than 1 mg at 1 to 2 week intervals based on the patient’s glucose response.
- Hypersensitivity to Glimepiride
- Pregnancy and breastfeeding
- Diagnosed with thyroid problems
- Allopurinol, Probenecid: increased risk of severely low blood sugar
- Aspirin, Fenofibrate, Insulin, Moclobemide, Phenelzine, Isocarboxazid, Tranylcypromine, Selegiline, Contraceptive pills, Thyroid medicines, Glucocorticoids: increased risk of severely low blood sugar
- Glimepiride 2 mg Tablet – Box of 100’s (in blister foil by 10’s)
- Glimepiride 3 mg Tablet – Box of 100’s (in blister foil by 10’s)